Chi. Cubs 13, Chi. White Sox 3
Pete Crow-Armstrong went 4-for-5 with a home run and six RBIs as the Chicago Cubs demolished the visiting Chicago White Sox 13-3 on Friday.
Cincinnati 5, Cleveland 4
Will Benson hit a three-run home run and Brady Singer pitched five solid innings as the host Cincinnati Reds beat the Cleveland Guardians 5-4 on Friday.
Philadelphia 8, Pittsburgh 4
Bryce Harper went 3-for-4 and drove in two runs, including the 1,000th of his career, as the Philadelphia Phillies rallied for a 8-4 victory over the visiting Pittsburgh Pirates on Friday night.
NY Yankees 6, NY Mets 2
Carlos Rodon pitched five innings and issued three walks to Juan Soto in the slugger's hostile return to Yankee Stadium as the host New York Yankees opened the Subway Series with a 6-2 victory over the New York Mets on Friday night.
Detroit 5, Toronto 4
Riley Greene had a solo homer and a two-run double as the visiting Detroit Tigers held on to defeat the Toronto Blue Jays 5-4 on Friday night.
Atlanta 4, Boston 2
Matt Olson and Sean Murphy hit back-to-back home runs in the second inning, and Chris Sale's seven innings of one-run ball made the blasts stand up as the visiting Atlanta Braves defeated the Boston Red Sox 4-2 on Friday night.
Miami 9, Tampa Bay 4
Connor Norby smacked a three-run double, leading the host Miami Marlins to a 9-4 win over the Tampa Bay Rays on Friday night in the opener of a three-game series.
St. Louis 10, Kansas City 3
Ivan Herrera had three hits with four RBIs, including a key three-run double in the sixth inning, while Andre Pallante allowed two runs over seven innings, as the surging St. Louis Cardinals won 10-3 over the struggling host Kansas City Royals on Friday night.
Houston 6, Texas 3
Christian Walker's three-run homer capped a six-run seventh inning as the Houston Astros finally woke up on offense and beat up on the Texas Rangers 6-3 on Friday in Arlington, Texas.
Minnesota 3, Milwaukee 0
Joe Ryan scattered two hits over six scoreless innings as the visiting Minnesota Twins extended their winning streak to 12 games with a 3-0 victory over the Milwaukee Brewers on Friday.
Arizona 8, Colorado 0
Corbin Burnes fanned 10 in six innings, Gabriel Moreno had three hits and scored three runs, and the Arizona Diamondbacks extended the Colorado Rockies' misery with an 8-0 victory on Friday in Phoenix.
Seattle 5, San Diego 1
J.P. Crawford homered on the game's first pitch, Rowdy Tellez and Cal Raleigh added long balls and the visiting Seattle Mariners topped the San Diego Padres 5-1 on Friday.
LA Angels 6, LA Dodgers 2
Yoan Moncada hit a first-inning home run and right-hander Jack Kochanowicz pitched into the seventh inning as the visiting Los Angeles Angels pulled off a 6-2 victory over the Los Angeles Dodgers on Friday to open a three-game series.
San Francisco 9, Athletics 1
Wilmer Flores set career highs with three homers and eight RBIs as the San Francisco Giants spoiled the Athletics' first return to the Bay Area representing West Sacramento with a 9-1 shellacking on Friday.